Pharmacokinetic and Pharmacodynamic Visualization System

*For Educational Use Only

Applied Medical Visualizations has developed a visual display system that can be used to accurately model the concentration and effect of anesthetic drugs administered alone and in combinations. This drug modeling system uses established Pharmacokinetic (Pk) and Pharmacodynamic (Pd) models to provide the clinician with the ability to visualize past and present states of sedation, analgesia and muscle relaxation. The clinician can also see the future status of these drug concentrations and the predicted effects of these drugs on the patient up to 15 minutes into the future. Analogous to a flight-path display for an airline pilot, the Pk/Pd display helps an anesthesiologist in the operating room to anticipate when levels of medication are adequate to relieve pain during surgery and accurately predict when the patient will wake up from the sedatives.

Benifits

• Accurate Pharmacokinetic and Pharmacodynamic information updated in real time
• Visual presentation of time based models for Sedation, Analgesia and Neuromuscular blockade
• PkPd data mapped to meaningful clinical endpoints such as
• Laryngoscopy
• Loss of Consciousness
• Return of Consciousness
• Response to Painful Stimulation (skin closure)
• Tuned to individual patient differences such as BMI, Age and Gender
• Models inhalation anesthetics
• Predictions of drug concentrations and effects 15 minutes into the future
• Represents synergistic effects of sedatives and opioid combinations